Natural history of familial cavernous malformations: CCM study
Part of Brain & nervous system, Genetic & congenital clinical trials.
This study follows people with a hereditary form of cavernous malformations (clusters of abnormal blood vessels in the brain). It aims to understand how the condition changes over time, without testing any new treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have familial cerebral cavernous malformations (FCCM) confirmed by a genetic test showing a change in the CCM1, CCM2, or CCM3 gene.
- You may have had symptoms like brain bleeds, strokes, seizures, or other neurological problems, or you may have no symptoms at all.
- You must be expected to live at least as long as the study lasts.
- You or your guardian must sign a form agreeing to take part.
- You cannot have a pacemaker or any other condition that would make an MRI scan unsafe.
- You cannot be in another interventional study, and you must be able to cooperate with the study procedures.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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