Psilocybin treatment for obsessive-compulsive disorder
Part of Mental health clinical trials.
This study tests whether a drug called psilocybin (the active ingredient in 'magic mushrooms') can help people with obsessive-compulsive disorder (OCD) who haven't found relief from standard treatments. It involves a few sessions with the drug under supervision, along with MRI scans and follow-up visits.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have been diagnosed with OCD, and it is at least moderate in severity.
- You have tried at least one standard OCD treatment that didn't work well enough.
- You are willing to stop taking current OCD medications and certain supplements for at least 2 weeks (and 6 weeks for fluoxetine).
- You have no history of psychosis in yourself or your immediate family.
- You have no medical conditions that could make the drug or MRI unsafe (like severe heart, kidney, or liver problems, or having certain implants).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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