Psilocybin Whole Mushroom for OCD Treatment
Treatments studied
Part of Mental health clinical trials.
This trial tests a whole-mushroom version of psilocybin as a potential treatment for OCD that hasn't improved with standard therapies. Participants receive psilocybin in a controlled setting and are monitored closely for safety and changes in symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have a diagnosis of moderate to severe OCD (Yale-Brown Obsessive Compulsive Scale score of 16 or higher) and have tried at least one standard treatment that didn't work.
- You cannot have any serious heart, lung, liver, kidney, or sleep apnea problems.
- You cannot have personal or family history of psychosis (like schizophrenia) or bipolar disorder.
- You must avoid certain medications and supplements (like antidepressants, mood stabilizers, and St. John's wort) for at least 2 weeks before starting the study.
- You cannot be pregnant, breastfeeding, or planning to become pregnant; and if you could become pregnant, you must use effective birth control during the study and for 3 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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