Clin2
NCT06995183Worth exploringRecruiting

Heart CT scan for relatives with high or low Lp(a)

Lipoprotein(a)

Part of Heart & circulation, Hormones & metabolism clinical trials.

This study uses a heart CT scan to look for early signs of heart disease in first-degree relatives of people with high or low Lp(a). It aims to find hidden risks before symptoms start.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
150 people
Ages
50 years and older
Study type
Observational

Who can take part

  • You must be 50 years old or older.
  • You must have a blood test result showing either very high Lp(a) (≥150 nmol/L) or very low Lp(a) (<50 nmol/L).
  • You were identified through family screening for high Lp(a) at the Amsterdam UMC Vascular Medicine clinic.
  • You must not have a history of heart disease, stroke, or blocked arteries.
  • You must not have used statins in the past or currently.
  • You must have normal kidney function (eGFR ≥30).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07382414Not yet recruiting
Electronic letters to boost heart health awareness

This trial tests whether simple electronic letters can motivate people with heart disease to better manage their health, especially their cholesterol levels. If you have high Lp(a) — a type of cholesterol linked to heart risk — you may also get a special letter about that.

Hellerup, Region Sjælland
NCT07613294Recruiting· Phase 3
Testing lepodisiran to reduce heart plaque buildup

This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.

La Jolla, California
NCT07184034Not yet recruiting
Lipoprotein a and heart scan risk

This study looks at whether a blood test for lipoprotein(a) can help predict heart disease risk when combined with a CT scan of the heart. If you are at intermediate risk for heart disease and are having a CT scan, this study may help you understand your risk better.

NCT07508007Recruiting
Study on improving Lp(a) testing in heart clinics

This trial tests ways to help doctors check for high Lp(a), a risk factor for heart disease, in patients who need it. The study looks at whether special strategies increase testing rates in cardiology centers that currently test less than 15% of eligible patients.

Nuremberg
NCT07640217Not yet recruiting· Phase 2
Study of an injected medicine for high lp(a) in adults

This study tests an investigational medicine given by injection to lower Lp(a), a type of fat linked to heart disease. It may help people with high Lp(a) who already have heart problems or are at increased risk.

NCT06858332Recruiting
Lp(a) cholesterol in adults with heart and blood vessel disease in Russia

This study looks at levels of a type of cholesterol called Lp(a) in people with certain heart and blood vessel diseases. The goal is to understand how common high Lp(a) is in Russian adults with these conditions.

Chelyabinsk

Hear when a new Lipoprotein(a) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.