Clinical trials
Lipoprotein(a) clinical trials
Below are recruiting lipoprotein(a) clinical trials, each written for real people, not researchers. We’re tracking 39 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07177612Enrolling by invitation
Testing the LILAC method for lipoprotein(a) education
This trial tests a new method called LILAC to help people learn about and manage high levels of lipoprotein(a), a type of fat in the blood. It is for anyone 16 or older who attends educational events or is part of a health group.
PerthAges 16 years+ - NCT07614984RecruitingPhase 2
Testing MK-7262 and Enlicitide for High Lipoprotein(a)
This trial tests two experimental drugs designed to lower lipoprotein(a)—a type of cholesterol particle linked to heart disease—in people whose levels remain high despite taking statins (cholesterol-lowering medications). The goal is to see if these drugs can safely reduce this risk factor.
Alexander City, AlabamaAges 18 years+ - NCT07324902Recruiting
How Lp(a) affects heart and blood vessel health
This study looks at how a fatty substance in your blood called lipoprotein(a), or Lp(a), might affect the stiffness of your arteries and how well your heart muscle works. It will help us understand if high Lp(a) is connected to early signs of heart disease.
Athens, AtticaAges 18–75 - NCT04227678Recruiting
Study of how fat is handled after eating in rare LPL deficiency
This study looks at how your body processes fatty acids after meals in people with lipoprotein lipase deficiency (a rare genetic condition). It also compares results to people without the condition, which may help researchers understand metabolism and guide future care.
Sherbrooke, QuebecAges 18–75 - NCT05962827Recruiting
Testing Lp(a) lipoprotein in people with lymphedema
This study looks at a blood marker called Lp(a) in adults who have lymphedema. The goal is to understand whether checking Lp(a) is important for people with this condition.
Nice, FranceAges 18–99 - NCT06014060Recruiting
Shorter vs. longer blood thinner therapy after stenting for high Lp(a)
This trial compares 12 months versus 24 months of dual antiplatelet therapy (two blood thinners) after a stent placement in people with high lipoprotein(a) levels. It aims to see if longer treatment reduces heart risks without increasing bleeding.
Beijing, Beijing MunicipalityAges 18–75 - NCT06439654Recruiting
Optimizing cholesterol treatment for heart health
This trial helps people with high cholesterol or a history of heart disease find the best treatment to lower their risk of future heart problems. It tests a program to optimize lipid-lowering therapy.
Clark, New JerseyAges 18–120 - NCT06995183Recruiting
Heart CT scan for relatives with high or low Lp(a)
This study uses a heart CT scan to look for early signs of heart disease in first-degree relatives of people with high or low Lp(a). It aims to find hidden risks before symptoms start.
Amsterdam, North HollandAges 50 years+ - NCT03372733RecruitingPhase 2
Omega-7 oil effects on blood fats and fullness
This study tests whether an omega-7 (palmitoleic acid–rich) oil changes your blood fat levels and how full you feel. It includes healthy adults and may help explain nutrition-based ways to support heart health.
Bethesda, MarylandAges 18–99 - NCT07136012RecruitingPhase 3
Olpasiran trial to lower Lp(a) and prevent first heart attack or stroke
This trial tests if olpasiran can lower a type of cholesterol called Lp(a) to help prevent a first major heart attack, stroke, or other heart problems. It is for people at higher risk due to risk factors or early signs of artery disease, but who have not yet had a heart attack or stroke.
Alexander City, AlabamaAges 50–105 - NCT07157774RecruitingPhase 3
Muvalaplin for heart disease in people with high lipoprotein(a)
This study tests a new medicine called muvalaplin that lowers a specific type of cholesterol linked to heart disease. It aims to see if muvalaplin can reduce the risk of future heart attacks, strokes, or related procedures in people with high levels of this cholesterol.
Apache Junction, ArizonaAges 18 years+ - NCT06482476Recruiting
Medical students' knowledge of cholesterol and lipoprotein(a)
This study asks medical students in Greece to share their understanding of high cholesterol and a related blood fat called lipoprotein(a). It helps researchers learn what future doctors know about these conditions.
Ioannina, IoanninaAges Any age - NCT06610669Recruiting
Study of high lipoprotein(a) levels in a registry
This is a registry study that looks at how common high lipoprotein(a) levels are. It helps researchers understand this condition better.
LodzAges Any age - NCT07327840RecruitingPhase 2
Study of Kylo-11 for heart disease with high Lp(a)
This trial tests a new drug, Kylo-11, for people with heart or blood vessel disease and high Lp(a), a type of cholesterol that raises risk of heart problems. The study will see if Kylo-11 can help lower that risk.
Los Angeles, CaliforniaAges 18–80 - NCT07517263RecruitingPhase 3
Long-term Safety Study of Pelacarsen Treatment
This study follows patients who completed an earlier pelacarsen trial to check if the treatment remains safe and well-tolerated over time. Pelacarsen is an experimental medicine being tested for heart and cholesterol health.
Andalusia, AlabamaAges 18–100 - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
La Jolla, CaliforniaAges 45–80 - NCT03512132Recruiting
Test HDL function in type 1 diabetes with kidney changes
This study looks at how well “good cholesterol” (HDL) works in people with type 1 diabetes, especially when kidney tests show early or more advanced damage. Researchers will compare different groups (normal, micro-, and macro-albumin in urine) to better understand HDL’s role and how it may relate to kidney health.
DijonAges 18 years+ - NCT05179954Recruiting
Blood fat testing study in adults with and without type 1 diabetes
This study measures how “blood fats” move in the body after fasting and controlled eating, comparing people with type 1 diabetes to those without diabetes. It may help researchers understand diabetes-related differences in lipid (fat) handling and improve future treatments.
Columbia, MissouriAges 18–45 - NCT05646381RecruitingPhase 2
Drug study to slow hardening of aortic valve disease
This Phase 2 trial tests pelacarsen (TQJ230), a medication that lowers a blood fat called lipoprotein(a), to see if it slows progression of calcific aortic valve stenosis. It may help people whose valve narrowing is starting to become more severe, especially when their lipoprotein(a) level is high.
Huntsville, AlabamaAges 50–80 - NCT05992688Recruiting
Sweet Kids Study: Stevia and Weight Over Time
This study tests whether replacing sugary drinks with stevia-sweetened drinks over time can help children manage their weight. Your child would drink the study beverages instead of their usual sugary drinks and have weight and health checks.
Little Rock, ArkansasAges 8–12 - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT06190834Recruiting
HDL subtypes and heart disease outlook study
This study looks at how different subtypes of HDL (the 'good' cholesterol) relate to the outlook for people with coronary artery disease. If you have heart artery blockages and your HDL subtypes have been checked, this trial might help understand your prognosis better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06649240Recruiting
Best LDL cholesterol goal after small vessel stroke
This trial is testing the best target for 'bad' cholesterol (LDL) after a type of stroke caused by a small blocked vessel. You would be in one of two groups to see which LDL level helps prevent another stroke the most.
AnsanAges 19 years+ - NCT07428473RecruitingPhase 1
Study of STX-1150 for high cholesterol
This early-phase trial tests a new medication called STX-1150 for people with high LDL cholesterol. It aims to see if the drug is safe and how well it works to lower cholesterol.
Clayton, VictoriaAges 18–70
Hear when a new Lipoprotein(a) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Lipoprotein(a) trials by city
Studies with a site in or near these metro areas.
Lipoprotein(a) trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for lipoprotein(a)?
- Yes. Clin2 currently lists 39 recruiting lipoprotein(a) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a lipoprotein(a) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a lipoprotein(a) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.