Radiofrequency ablation for obstructive hypertrophic cardiomyopathy
Part of Heart & circulation clinical trials.
This trial tests a new treatment that uses radiofrequency energy (similar to heat) to shrink the thickened heart muscle blocking blood flow. It is for people with obstructive hypertrophic cardiomyopathy who have symptoms despite medication and are not able or willing to have heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have a type of thickened heart muscle that blocks blood flow (obstructive hypertrophic cardiomyopathy).
- You have symptoms like shortness of breath, chest pain, or fatigue that affect your daily life.
- Your heart blockage is at least 50 mmHg (a measure of pressure) and you are in New York Heart Association class II or higher.
- The thickened part of your heart is at least 15 mm thick.
- You are not eligible for or you choose not to have heart surgery to fix the blockage.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial looks at how the heart's electrical signals work in people with hypertrophic cardiomyopathy (a condition where the heart muscle becomes thickened) who also have atrial fibrillation (a type of irregular heartbeat). The goal is to understand these signals better during a planned ablation procedure, which is a treatment to fix the irregular rhythm.
This trial combines a new heart medication (mavacamten) with a procedure called radiofrequency ablation to treat a condition where the heart muscle thickens and blocks blood flow. It is for people who still have symptoms despite standard care.
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