Thyroid hormone for lack of motivation in schizophrenia
Part of Mental health clinical trials.
This trial tests whether adding a thyroid hormone called thyroxine to your usual medication can help with lack of motivation, a common symptom in schizophrenia. You would need to be stable on your current antipsychotic and not have any thyroid problems.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a diagnosis of schizophrenia and are between 18 and 45 years old.
- You are right-handed.
- Your symptoms are stable with the same antipsychotic medication dose for at least 4 weeks.
- You have significant lack of motivation but mild positive symptoms (like hallucinations or delusions).
- You are not taking clozapine or first-generation antipsychotics, and do not have thyroid disease.
- You can have an MRI scan (no metal implants or claustrophobia).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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