Exercise therapy for weakness after sepsis in the ICU
Part of Brain & nervous system clinical trials.
This trial tests whether adding physical therapy early in the ICU can help people with sepsis regain strength and reduce muscle weakness. It focuses on patients who need a breathing tube for at least a week and have a high level of organ failure.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You were diagnosed with sepsis when you entered the ICU
- You are on a breathing machine and expected to need it for at least 7 days
- Your organ failure score (SOFA) was high (8 or more) for three days in a row during your first 5 days in the ICU
- You do not have long-term muscle or nerve disease, severe liver disease, or need dialysis
- You are not pregnant and your body mass index is less than 35
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if a walking program combined with electrical stimulation can help people recover walking ability after critical illness. It is for patients who developed limb weakness in the hospital and were independent before their illness.
This study looks at blood and body chemistry (called metabolomics) to understand and possibly predict muscle weakness that can happen in the ICU after surgery. It may help researchers find better ways to prevent or monitor this problem.
This trial tests whether a device that delivers small electrical pulses to muscles can help prevent breathing and muscle weakness in very sick ICU patients. It also looks at changes in blood markers that may relate to muscle weakness and recovery.
This trial looks at how to improve muscle strength and function after a stay in the ICU for sepsis or acute respiratory failure. If you recover from the illness but your muscles become weak, this study may test an approach to help rebuild strength faster.
This trial tests a wearable device that uses mild electrical pulses to stimulate leg muscles, helping prevent muscle weakness in ICU patients with severe infections. It may help you recover strength faster and avoid long-term disability.
This study is for people in the ICU with sepsis who need a breathing machine for a long time. It monitors muscle changes during recovery to understand how sepsis affects muscles.
Hear when a new Critical Illness Myopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.