Novosis Putty for spine fusion in lumbar disc disease
Part of Bones, joints & muscles clinical trials.
This trial tests a new bone graft putty (Novosis Putty) used during a specific type of spine fusion surgery (TLIF) to treat a worn-out disc causing low back and leg pain. The goal is to see if it works as well as or better than current options.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have ongoing lower back pain from a worn-out disc between the L1 and S1 vertebrae, and imaging shows this is the main problem.
- You have tried at least 6 months of non-surgical treatments (like physical therapy, medications, or injections) without enough relief.
- Your back and leg disability score is at least 40 out of 100 on a standard questionnaire (Oswestry Disability Index).
- You are between 21 and 80 years old and in generally good health for surgery.
- You have not had previous spine surgery (like fusion or disc replacement) at the same level that would be treated now.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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