Doxapram to help COPD patients breathe easier off the ventilator
Treatments studied
Part of Lungs & breathing clinical trials.
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have moderate to severe COPD
- You are currently on a ventilator and ready for a spontaneous breathing trial
- You do not have an allergy to doxapram
- You do not have a neuromuscular disorder (a condition affecting nerves and muscles)
- Your doctor can assess your diaphragm with ultrasound or similar test
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a personalized pacing device that uses ultrasound to help your diaphragm muscle work better while you are on a breathing machine. It may help you breathe on your own sooner and improve your recovery.
This study uses a special ultrasound technique to look at how your diaphragm (the main breathing muscle) moves while you try breathing on your own. It may help doctors better understand when patients are ready to come off the breathing machine.
This trial studies how well your diaphragm (the main breathing muscle) works during a severe COPD flare, using an ultrasound scan. It may help doctors better assess breathing muscle performance when COPD symptoms suddenly worsen.
This trial tests whether adding arm and shoulder exercises to standard breathing muscle training helps people on ventilators wean off more successfully. It may improve your ability to breathe on your own.
This study tests whether a gentle electrical stimulation on your diaphragm (the muscle that helps you breathe) combined with deep breathing exercises can improve your breathing and quality of life. It is for people with mild to moderate COPD who do not smoke and have a chronic cough with mucus.
This study tests whether using ultrasound (sound waves) to look at your diaphragm (the muscle that helps you breathe) can help doctors decide the right time to take you off a breathing machine. If you have COPD and are on a ventilator, this could help you get off the machine sooner and more safely.
Hear when a new COPD trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.