Combining clot removal and tirofiban for stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests adding the anti-clotting drug tirofiban to standard clot removal for people who have a stroke due to a narrowed artery in the brain. The goal is to see if this combination improves outcomes without raising bleeding risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stroke and can get treatment within 24 hours of when symptoms started.
- You can still do most daily activities on your own before this stroke.
- Your stroke is caused by a blockage in a large artery in the front or back of the brain.
- Your doctor plans to do a procedure (clot removal) to open the blocked artery.
- You have not had recent major bleeding or surgery, and do not have a bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether adding a second medicine (tirofiban) to standard clot-busting treatment can help people who are not improving after the first hour. It is for people with a moderate to severe stroke who are not candidates for a clot-removal procedure.
This trial tests whether adding a medicine called tirofiban (which helps prevent blood clots) after standard stroke treatment can improve recovery in people who had a stroke due to a blocked large artery in the brain. It is for people who already received a clot-busting drug and a mechanical clot removal procedure, and who have not fully recovered.
This trial tests whether giving a medication called tirofiban directly into the artery (intra-arterially) after a successful clot removal can improve recovery after a stroke. Tirofiban helps prevent new clots from forming, which may reduce the chance of another stroke.
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This study tests whether giving the blood-thinning drug tirofiban for a shorter or longer time after standard clot-busting treatment improves recovery from a stroke. It aims to find the best duration to prevent further damage while avoiding side effects.
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