Combining clot removal and tirofiban for stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests adding the anti-clotting drug tirofiban to standard clot removal for people who have a stroke due to a narrowed artery in the brain. The goal is to see if this combination improves outcomes without raising bleeding risk.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stroke and can get treatment within 24 hours of when symptoms started.
- You can still do most daily activities on your own before this stroke.
- Your stroke is caused by a blockage in a large artery in the front or back of the brain.
- Your doctor plans to do a procedure (clot removal) to open the blocked artery.
- You have not had recent major bleeding or surgery, and do not have a bleeding disorder.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests whether adding a second medicine (tirofiban) to standard clot-busting treatment can help people who are not improving after the first hour. It is for people with a moderate to severe stroke who are not candidates for a clot-removal procedure.
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This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
This trial tests whether injecting a blood thinner called tirofiban directly into brain blood vessels during a stroke procedure helps prevent clots from forming again. If you've had a stroke caused by a large clot in your brain that was successfully removed, this study may help protect your recovery.
This trial tests whether starting tirofiban soon after tenecteplase can improve outcomes for people whose stroke symptoms temporarily get worse after treatment. It aims to see if the added medicine can reduce harmful clot-related changes after initial thrombolysis.
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