Using a brain protection device during TAVR to prevent stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests if a special device placed during transcatheter aortic valve replacement (TAVR) can help prevent stroke. It is for adults with severe aortic stenosis who are already scheduled for TAVR.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe narrowing of your aortic valve (aortic stenosis) that causes symptoms.
- You are scheduled to have TAVR (a procedure to replace the valve through a catheter in your leg).
- You will receive the Sentinel Cerebral Protection System during the procedure.
- You are an adult who agrees to participate and signs a consent form.
- You have not had a stroke, brain bleed, brain tumor, encephalitis, or other brain disease in the last year.
- You have not had open-chest surgery or a previous heart valve replacement.
- Your heart's pumping strength (left ventricular ejection fraction) is above 30%.
- You can have an MRI scan and do not have severe claustrophobia.
- You are willing and able to attend follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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