Deep brain stimulation for severe tremor
Part of Brain & nervous system clinical trials.
This trial tests a new type of deep brain stimulation (DBS) for people with severe tremor from essential tremor, multiple sclerosis, or cerebellar conditions who haven't improved with standard treatments. It targets a different brain area to see if it can reduce shaking and improve daily activities.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 years or older.
- You have essential tremor, cerebellar tremor, or MS-related tremor for at least 3 years.
- Standard treatments like VIM DBS or focused ultrasound haven't worked or aren't right for you.
- Your tremor doesn't improve enough with medications.
- You struggle with daily tasks or have given up social or work activities due to tremor.
- You are able to give informed consent and have no severe memory problems or untreated depression.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at how deep brain stimulation (DBS) affects brain networks in people with essential tremor (ET). The goal is to understand the brain changes that happen during DBS treatment, which may help improve the therapy.
This study tests a new way to use Deep Brain Stimulation (a device that sends tiny electrical pulses to parts of the brain controlling movement) for people with Essential Tremor. It is for those whose current stimulator is no longer working well, or who need a stimulator for the first time.
This Phase 1 study tests a coordinated reset deep brain stimulation program for people with essential tremor. It may help reduce tremor symptoms using a specific implanted brain-stimulation device, along with special high-strength MRI and CT imaging before and after surgery.
This study looks at how brain “wiring” (connectivity) and brain function change over time in people with essential tremor after successful deep brain stimulation. You might benefit by helping researchers better understand what DBS does in the brain, which can improve care for others with tremor.
This study collects information from adults with essential tremor who are getting deep brain stimulation under the hospital’s standard safety guidelines. It may help improve how this treatment is chosen and used for people with tremor over time.
This trial tests an upgraded deep brain stimulation (DBS) system that can “sense” tremor and adjust treatment in a loop. It’s designed for people with severe essential tremor whose tremor is still disabling despite standard DBS and medication.
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