Clin2
NCT04758624Possibly a fitRecruiting

Study brain changes after deep brain stimulation for tremor

Essential Tremor

Part of Brain & nervous system clinical trials.

This study looks at how brain “wiring” (connectivity) and brain function change over time in people with essential tremor after successful deep brain stimulation. You might benefit by helping researchers better understand what DBS does in the brain, which can improve care for others with tremor.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
72 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You have been diagnosed with essential tremor by a movement-disorders neurologist, not caused by another illness or injury.
  • Your tremor is mainly in your hands/arms (distal), with little tremor closer to the body (proximal).
  • Medication didn’t work well enough and/or side effects were too hard to tolerate.
  • Your tremor greatly affects your daily life or quality of life.
  • You must have no major safety blockers for deep brain stimulation surgery.
  • You should not be pregnant, and you should not have had metal objects in your body that “float” (like certain metal fragments).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06293638Recruiting
Brain changes during deep brain stimulation for essential tremor

This study looks at how deep brain stimulation (DBS) affects brain networks in people with essential tremor (ET). The goal is to understand the brain changes that happen during DBS treatment, which may help improve the therapy.

Cleveland, Ohio
NCT06325852Recruiting
New brain stimulation for Essential Tremor

This study tests a new way to use Deep Brain Stimulation (a device that sends tiny electrical pulses to parts of the brain controlling movement) for people with Essential Tremor. It is for those whose current stimulator is no longer working well, or who need a stimulator for the first time.

Toronto, Ontario
NCT07049003Recruiting· Phase 1
Deep brain stimulation for severe tremor

This trial tests a new type of deep brain stimulation (DBS) for people with severe tremor from essential tremor, multiple sclerosis, or cerebellar conditions who haven't improved with standard treatments. It targets a different brain area to see if it can reduce shaking and improve daily activities.

Cleveland, Ohio
NCT04032470Recruiting
Deep brain stimulation registry for essential tremor patients

This study collects information from adults with essential tremor who are getting deep brain stimulation under the hospital’s standard safety guidelines. It may help improve how this treatment is chosen and used for people with tremor over time.

Innsbruck
NCT05897775Recruiting· Phase 1
Testing a new deep brain stimulator approach for essential tremor

This Phase 1 study tests a coordinated reset deep brain stimulation program for people with essential tremor. It may help reduce tremor symptoms using a specific implanted brain-stimulation device, along with special high-strength MRI and CT imaging before and after surgery.

Minneapolis, Minnesota
NCT04828798Recruiting
Directional versus standard brain stimulation for essential tremor

This study compares two ways of delivering deep brain stimulation (DBS) to treat essential tremor that affects both arms. It may help find a DBS approach that better controls tremor while reducing side effects.

Portland, Oregon

Hear when a new Essential Tremor trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.