Sleep stimulation to boost brain waste clearance
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether stimulating the brain during sleep can help clear waste proteins, like amyloid, that build up in the brain and are linked to memory problems. If you have early memory issues or are a healthy adult, you may be able to participate.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 55 and 80 years old if you have memory concerns, or between 18 and 80 if you are healthy.
- If you have memory concerns, a doctor must have confirmed amyloid buildup in your brain (via PET scan or spinal fluid test).
- You need to be fluent in French to complete the cognitive tests.
- You must be able to have an MRI scan (no metal implants, pacemaker, or other electronic devices in your body).
- You cannot have current or past psychiatric or neurological conditions, untreated sleep disorders, or irregular sleep-wake cycles.
- You cannot be taking psychotropic medications (like benzodiazepines or antidepressants) or regularly drinking alcohol or caffeine in excess.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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