TAVI's effect on gut bacteria in aortic stenosis
Part of Heart & circulation clinical trials.
This study looks at how a heart valve procedure called TAVI affects the bacteria in your gut. It may help doctors understand how the procedure impacts your overall health.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have severe aortic stenosis that your doctor says can be treated with a TAVI procedure.
- You have not taken antibiotics, steroids, antivirals, probiotics, or any new medications in the last month.
- You do not have inflammatory bowel disease (like Crohn's or ulcerative colitis).
- You are not on dialysis for kidney failure, and you do not have end-stage liver disease.
- You do not have an active infection, untreated cancer, or a history of substance abuse.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial is for people with severe aortic stenosis who are already scheduled for TAVI (a procedure to replace a narrowed heart valve). It looks at how individual differences affect the procedure's outcomes.
This study looks at whether pressure readings taken during a heart procedure can help predict how well patients with severe aortic stenosis improve after getting a new aortic valve (TAVI). It aims to find better ways to track progress using standard pressure measurements.
This study looks for biological markers in the blood that might help predict heart-related events in people with a narrowed aortic heart valve. It aims to improve care for those with this condition, whether or not they have a procedure called TAVI to replace the valve.
This trial tests a minimally invasive procedure called TAVI (transcatheter aortic valve implantation) to replace a narrowed aortic valve without requiring open-heart surgery. The study is checking whether TAVI can be safely performed at hospitals that don't have cardiac surgery units on-site.
This trial tests if a heart valve replacement procedure called TAVI can be safely done at heart centers that do not have a full heart surgery team available onsite. It is for people with severe narrowing of the aortic valve who are already planned for TAVI through the leg artery.
This study looks at how gut bacteria might be linked to a hardened heart valve (calcified aortic stenosis). Participants will provide blood and stool samples to help researchers understand this connection.
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