Locus Coeruleus study in Ondine syndrome patients
Part of Brain & nervous system, Lungs & breathing, Mental health clinical trials.
This study looks at a small part of the brain called the locus coeruleus in people with Ondine syndrome (also called congenital central hypoventilation syndrome). It aims to understand how this brain area works in people who need nighttime breathing support.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with Ondine syndrome at birth.
- Have a specific type of PHOX2B gene change (PARM-type).
- Between 7 and 20 years old.
- Use a breathing machine (ventilator) at night.
- Not have severe autism that interferes with testing.
- Be able to consent (or have a parent consent) and be part of French social security.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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