Brain breathing center study in children with Ondine syndrome
Part of Brain & nervous system, Lungs & breathing, Mental health clinical trials.
This study looks at how a part of the brain called the locus coeruleus, which controls breathing, works in children with Ondine syndrome (a rare condition where breathing is not automatic, especially during sleep). It aims to understand how this brain area relates to the condition, which may help improve future care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Diagnosed with Ondine syndrome (a rare condition that affects breathing) at birth
- Carry the PARM type of PHOX2B gene mutation
- Age between 7 and 20 years
- Use a breathing machine at night (nocturnal ventilation)
- Does not have severe autism that would interfere with testing
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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