Pentoxifylline for liver growth after donor surgery
Treatments studied
Part of Digestive system clinical trials.
This study tests if a medicine called pentoxifylline can help your liver grow faster after donating a large part of it. You would take the medicine before and after your donor surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a healthy person donating part of your liver (a live donor).
- You are scheduled to have your right liver lobe removed (right donor hepatectomy).
- You are not allergic to pentoxifylline.
- You give your informed consent to take part in the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving ursodeoxycholic acid (a bile acid medication) after a living donor liver transplant helps the new liver grow and work better. It may help your liver recover more quickly.
This trial studies a way to help people who need liver surgery but have a very small remaining liver after the operation. It tests a special growth observation approach to see if it can safely increase the size of the future liver remnant.
This study tests a generic version of the drug pentoxifylline (a tablet) to see if it works the same as the brand name. You will take the drug once and have blood samples taken over time. It's for healthy volunteers to help make sure the generic is safe and effective.
This trial tests whether a medication (octreotide) or a minor surgical procedure (tying off a spleen artery) works better to help a smaller-than-ideal liver graft work well after a living donor transplant. The goal is to improve blood flow and prevent complications.
This study looks at how the donor's liver grows back after donating a part of it for a living donor liver transplant. If you have donated a part of your liver between 2004 and 2026, joining could help doctors learn more about liver healing.
This trial tests if a machine that pumps warm oxygenated blood through livers that were considered unsuitable for transplant can help doctors decide if they are actually safe to transplant. If so, it could increase the number of available livers for people waiting for a first liver transplant.
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