GeminiOne Clip for Severe Mitral Regurgitation
Part of Heart & circulation clinical trials.
This trial tests a new device called GeminiOne that clips together part of your leaky mitral valve to reduce backward blood flow. It is for people with severe mitral regurgitation who are not candidates for open-heart surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You have severe mitral regurgitation (a leaky mitral valve) confirmed by a special heart ultrasound.
- Your heart doctor and a study team agree that you are not a good candidate for standard mitral valve surgery, and for secondary MR, you have tried medications without success.
- Your mitral valve anatomy is suitable for a clip procedure called TEER with the GeminiOne device, and you have no major blockages, severe calcification, or other valve problems that would make the procedure risky.
- You do not have severe kidney failure, active infection, recent heart attack or stroke, or a life expectancy under 12 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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