Clin2
NCT07089251Possibly a fitRecruiting

Epinephrine and tranexamic acid in knee replacement surgery

Knee Arthroplasty, TotalKnee Arthritis, OsteoarthritisTotal Knee AnthroplastyBlood LossTranexamic Acid UseEpinephrine

Part of Bones, joints & muscles clinical trials.

This study tests if using epinephrine and tranexamic acid together helps reduce bleeding and improve outcomes during knee replacement surgery. It may be a good fit if you are planning to have knee replacement and do not have certain medical conditions or allergies to these medicines.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
80 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are scheduled for knee replacement surgery.
  • You have a complete medical record available.
  • You do not have serious kidney or liver disease.
  • You do not have a history of blood clots, stroke, or heart attack in the past year.
  • You are not pregnant or breastfeeding.
  • You are not allergic to epinephrine or tranexamic acid.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07853885Not yet recruiting· Phase 4
Tranexamic acid in bone to reduce bleeding during knee replacement

This study tests whether putting tranexamic acid (a medicine that helps blood clot) directly into the bone during knee replacement surgery can reduce blood loss. It may help people recover with less need for blood transfusions.

Kunming, Yunnan
NCT07494032Not yet recruiting
Extended tranexamic acid after total knee replacement

This study tests whether taking tranexamic acid (a medication that helps blood clot) for a few days after knee replacement surgery can reduce bleeding and the need for blood transfusions. It may help patients recover with fewer complications.

New York, New York
NCT06618820Enrolling by invitation· Phase 3
Extended tranexamic acid after knee replacement

This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.

Germantown, Tennessee
NCT06479161Recruiting· Phase 2
Oral tranexamic acid study for knee replacement patients

This trial tests if taking tranexamic acid (TXA) as a pill can reduce bleeding after total knee replacement surgery. It may help you if you have knee osteoarthritis and are scheduled for a first-time knee replacement.

Hartford, Connecticut
NCT07614087Not yet recruiting· Phase 4
Bleeding medicine during hip or knee replacement

This study measures how a medicine called tranexamic acid (which helps reduce bleeding) works when given through a needle in the bone versus in a vein during hip or knee replacement surgery. It may help your surgeon choose the best way to control bleeding during your operation.

Linhai, Zhejiang
NCT06894719Not yet recruiting· Phase 4
Tranexamic acid after knee replacement to reduce bleeding and pain

This study tests whether taking tranexamic acid for up to seven days after knee replacement surgery can reduce swelling, pain, and the need for pain pills. It may help you recover more comfortably after your operation.

Hear when a new Knee Arthritis Osteoarthritis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.