Testing riluzole delivered by pump for ALS
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests a new way of giving riluzole, a medicine already used for ALS, by delivering it directly into the fluid around the spinal cord using a small pump. It aims to see if this method is safe and might work better for people with ALS.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You can walk, with or without a cane or walker.
- You have been diagnosed with ALS (sporadic or familial) that is not bulbar-onset.
- Your breathing strength is at least 70% of what is expected for your age, gender, and height.
- You are able to have a small pump implanted under your skin, or you already have a pump in place.
- You are currently taking riluzole by mouth (50 mg twice a day) and have been for at least 30 days.
- You do not have bleeding risks, infections, or other serious medical conditions that would make the pump unsafe.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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