Cyclophosphamide for ALS symptoms
Treatments studied
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests whether a medicine called cyclophosphamide can slow the progression of ALS. It's given to people who have had symptoms for less than 2 years and still have good breathing, to see if calming the immune system can help protect nerve cells.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have a confirmed diagnosis of ALS by a specialist.
- Your ALS symptoms have been getting worse at a moderate pace over the last 12 weeks (roughly 1 to 4 points on a standard scale).
- Your first symptoms started less than 2 years ago.
- You have good breathing strength (at least 70% of what's expected for your age and size).
- You are willing to undergo a brain PET scan and agree to receive cyclophosphamide, a drug that calms the immune system.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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