Testing OriV508 for blood cancers that haven't responded to treatment
Part of Blood & lymphatic, Cancer, Heart & circulation, Immune system & allergy clinical trials.
This study tests a new treatment called OriV508 for people with blood cancers (multiple myeloma or aggressive B-cell lymphoma) that have not responded to at least two previous therapies. It aims to see if the treatment is safe and helps shrink or control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have multiple myeloma or an aggressive B-cell lymphoma that has come back or not responded after at least 2 treatments.
- You are able to do most daily activities without help.
- Your blood counts (like white blood cells, hemoglobin, and platelets) are within safe limits.
- Your major organs (heart, lungs, kidneys, liver) are working well enough based on simple tests.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a new type of CAR-T cell therapy called OriCAR-017 for people with multiple myeloma that has come back or not responded to treatment. It is for patients who have already tried several treatments, including ones that target BCMA, and their last treatment stopped working.
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