Studying a medicine to preserve muscle during weight loss
Treatments studied
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests a new medicine, (S)-pindolol benzoate, given along with semaglutide (Ozempic/Wegovy). The goal is to see if it helps people lose mostly fat instead of muscle while on a weight loss program.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be eligible to take semaglutide, a medicine used for weight loss.
- Your BMI (body mass index) must be 30 or higher.
- If you have type 2 diabetes, you cannot have taken semaglutide or similar GLP-1 medicines in the past 3 months, had a low blood sugar event, lost more than 11 pounds, or had an HbA1c over 10.0% within that time.
- You cannot have had a heart attack, stroke, chest pain, or heart failure in the last year.
- You cannot have severe chronic lung disease (COPD).
- You cannot be taking beta blockers, and you must not have any reason that beta blockers are unsafe for you.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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