Testing low-dose osilodrostat for mild cortisol excess
Treatments studied
Part of Cancer, Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests whether a low dose of the drug osilodrostat can help people with mild cortisol excess (MACS) caused by benign adrenal tumors. It may improve related health problems like high blood pressure, diabetes, or bone thinning.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with mild cortisol excess (MACS) based on a special test done in the last 2 years.
- You have a benign adrenal tumor or adrenal overgrowth seen on imaging.
- You have at least one related health issue such as obesity, diabetes, high cholesterol, high blood pressure, or bone thinning.
- You are able to take oral medication and follow the study schedule.
- If you could become pregnant, you agree to use effective birth control or abstain from sex during treatment and for 1 month after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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