Metyrapone study for mild cortisol excess
Part of Cancer, Genetic & congenital, Hormones & metabolism, Kidney & urinary, Women’s health & pregnancy clinical trials.
This study tests if a medication called metyrapone can help people with mild autonomous cortisol secretion (MACS), a condition where your body makes too much cortisol. It looks at whether the drug improves related health problems like high blood pressure, diabetes, or bone issues.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have mild autonomous cortisol secretion (MACS) confirmed by a dexamethasone suppression test in the last 2 years
- You have an adrenal adenoma or adrenal hyperplasia seen on imaging
- You have at least one related condition: obesity, high blood sugar, high cholesterol, high blood pressure, or bone thinning/fractures
- You can take pills and follow the study plan
- You agree to use effective birth control if you could become pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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