Brain structure changes in schizophrenia and nicotine dependence
Part of Mental health clinical trials.
This study uses special brain scans (MRI) to look at the structure of the brain in people with schizophrenia, comparing smokers and non-smokers. It may help doctors understand how nicotine dependence affects the brain in schizophrenia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have been diagnosed with schizophrenia and are stable on your current medication for at least 2 months.
- If you are in the smoking group, you must be dependent on nicotine (as determined by a standard questionnaire). Non-smokers can also join as a comparison group.
- You do not have any other major psychiatric or neurological condition, severe head injury, or current substance abuse (other than nicotine).
- You are able to undergo an MRI scan (no metallic implants, no severe claustrophobia that would make the scan impossible).
- You can provide written consent, or your caregiver can consent on your behalf.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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