Testing a PCSK9 inhibitor for recent stroke from brain artery narrowing
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether a cholesterol-lowering medication (PCSK9 inhibitor) can help prevent further strokes in people who have recently had a stroke or mini-stroke due to a narrowed artery in the brain. It is for adults 30 to 80 years old who meet specific health criteria.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 30 and 80 years old.
- If you are between 30 and 49, you must have diabetes for at least 15 years, or have multiple risk factors like high blood pressure, high cholesterol, smoking, or a family history of heart disease or stroke.
- You have had a stroke or a high-risk mini-stroke (TIA) in the last 7 days.
- You have a narrowed artery in the brain (more than 50%) that caused your symptoms.
- Your stroke or mini-stroke is not caused by a heart problem, a tear in the artery, or other specific conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether a PCSK9 inhibitor (a drug that lowers cholesterol) can help people who recently had a stroke caused by narrowing of an artery inside the skull. It aims to see if the drug can prevent more strokes and improve recovery.
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This trial tests if adding a PCSK9 inhibitor (a newer cholesterol-lowering medicine) to standard care helps people who had a stroke from a large artery blockage and had a clot-removal procedure. It may lower bad cholesterol further and reduce the risk of another stroke.
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This study looks at strategies to improve cholesterol treatment in adults whose brain arteries are narrowed and who have had symptoms. Better cholesterol management may help reduce future problems related to this condition.
This trial tests whether a cholesterol-lowering medication called evolocumab (a PCSK9 inhibitor) can help people recover better after a specific type of stroke caused by clogged arteries. The study checks if lowering cholesterol further than usual statins do improves stroke outcomes and is safe.
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