Clinical trials
Radiofrequency Ablation clinical trials
Below are recruiting radiofrequency ablation clinical trials, each written for real people, not researchers. We’re tracking 114 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07509593Recruiting
Comparing two types of tailbone pain treatment
This study compares two types of a targeted procedure (radiofrequency ablation) to treat long-lasting tailbone pain. It is designed for people who have already gotten good relief from a nerve block injection but whose pain has come back.
Istanbul, PENDİKAges 18–75 - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Atlanta, GeorgiaAges 18 years+ - NCT06716294Recruiting
Radiofrequency ablation and stabilization for spine tumors
This trial tests a treatment that uses heat to destroy active spine tumors from cancer that has spread, followed by stabilizing the bone. It aims to see if the treatment works by using a special scan (PET-CT) to confirm the results.
Athens, AthensAges 18–90 - NCT07728539Recruiting
Comparing a faster ablation method for atrial fibrillation
This study compares a newer, faster type of ablation (high-power short-duration) with the standard approach for treating atrial fibrillation. The goal is to see which method is safer and more effective at restoring a normal heart rhythm.
MoscowAges 18–70 - NCT04150744RecruitingPhase 2
New immune drug plus immunotherapy for liver cancer
This Phase 2 trial tests whether adding a new drug (RFA) to an immunotherapy medicine (carrizumab) works better than carrizumab alone for hepatocellular carcinoma, a type of liver cancer. It may help people whose tumors cannot be removed or transplanted and who have not started whole-body (systemic) cancer treatment yet.
Hangzhou, ZhejiangAges 18–75 - NCT05991856Recruiting
Comparing ablation vs. surgery for adrenal tumors causing high blood pressure
This trial compares two treatments—ultrasound-guided ablation and laparoscopic adrenalectomy—for a type of adrenal tumor called aldosterone-producing adenoma (APA) that causes high blood pressure and low potassium. The goal is to see which treatment works better for patients with a single, non-cancerous tumor.
Guangzhou, GuangdongAges 18 years+ - NCT06052098Recruiting
Comparing two ablation methods for early-stage lung cancer
This study compares two ways to destroy early-stage lung cancer without surgery: one using a needle through the chest (CT-guided) and another using a thin tube through the mouth (bronchoscopy-guided). It might be an option if you have small, outer-edge lung cancer and cannot or prefer not to have surgery.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06791915Recruiting
Comparing breathing method during heart ablation for AFib
This trial studies two ways of using a breathing machine during a heart procedure called radiofrequency ablation for atrial fibrillation (AFib). It aims to find which method is better and safer.
KocaeliAges 18 years+ - NCT06914960Recruiting
Ultrasound-guided nerve radiofrequency for knee pain
This trial tests a treatment that uses radio waves to reduce pain signals from the nerves around the knee. It might help if you have long-lasting knee pain from osteoarthritis and find certain movements very painful.
Ankara, AnkaraAges 30–75 - NCT07141745Recruiting
Comparing energy types for repeat atrial fibrillation treatment
This trial compares two different energy methods (electroporation vs radiofrequency ablation) guided by 3D imaging for people who have had a prior ablation for atrial fibrillation but still have recurrences. It aims to find which method is safer and more effective for repeat procedures.
WroclawAges 18–85 - NCT07209397Recruiting
Radiofrequency treatment for overactive bladder in women
This trial tests a new procedure that uses radiofrequency energy to calm the nerve responsible for overactive bladder in women. It aims to reduce urge-related urine leaks without surgery or medications.
Palo Alto, CaliforniaAges 22–80 - NCT07470580Recruiting
Heat treatment vs surgery for adrenal gland tumor
This study compares two treatments for a certain type of adrenal gland tumor (Conn's adenoma) that causes high blood pressure. One is a heat-based procedure called radiofrequency ablation and the other is surgery to remove the tumor. The goal is to see which is better at controlling blood pressure.
ToulouseAges 18 years+ - NCT07536087Recruiting
Heat treatment for pancreatic cysts and neuroendocrine tumors
This trial tests a minimally invasive endoscopic procedure that uses heat to treat certain pancreatic cysts (fluid-filled sacs) and small neuroendocrine tumors (hormone-producing growths). It may be an option if surgery isn't possible or if you prefer to avoid it.
PragueAges 18 years+ - NCT07601763Recruiting
Pulsed Field Ablation for Atrial Fibrillation Treatment
This trial tests a newer ablation technique called pulsed field ablation to treat atrial fibrillation, a heart rhythm disorder. The goal is to see if this method works well and is safe for patients who need treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04823299Recruiting
Atrial fibrillation ablation using two different energy types
This trial tests whether one ablation approach works better than another for paroxysmal (intermittent) atrial fibrillation by targeting the heart’s “triggers” and “substrate” (where the rhythm problem is). If you qualify, you’ll be randomly assigned to one of two ablation energy methods during a pulmonary vein isolation procedure.
Ottawa, OntarioAges 18 years+ - NCT07206121Recruiting
Study of a new device for breast cancer surgery
This trial tests a device that uses radiofrequency energy to help remove breast cancer during surgery. It may be an option for women over 50 with a specific type of early-stage breast cancer.
Galveston, TexasAges 50 years+ - NCT06711120Recruiting
Comparing two treatments for varicose veins in the lower legs
This study compares two minimally invasive treatments (radiofrequency ablation and microwave ablation) for varicose veins in the small saphenous vein. If your varicose veins cause symptoms like pain, swelling, or heaviness, this trial may help determine which treatment works better.
ChengduAges 18–90 - NCT07126535Recruiting
Radiofrequency ablation effects on the esophagus
This study looks at how radiofrequency ablation (RFA) affects the flexibility and lining of the esophagus in people with Barrett's esophagus and early cancer. It may help doctors understand how this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT07233616Recruiting
Radiofrequency ablation for chronic venous insufficiency in patients 80+
This study tests whether a procedure called radiofrequency ablation (using heat to close faulty veins) is safe and effective for people aged 80+ with chronic venous insufficiency. It aims to relieve symptoms like leg swelling, skin changes, or ulcers.
Chengdu, SichuanAges 80 years+ - NCT05638841Recruiting
Study of repeat atrial fibrillation risk after ablation
This study follows adults who have had a procedure to treat an irregular heartbeat, to understand who is more likely to have it return. It may help doctors predict risk and plan follow-up after the procedure.
BeijingAges 18 years+ - NCT06647251Recruiting
Comparing different radiofrequency modes for atrial fibrillation ablation
This trial tests three different ways of delivering radiofrequency energy using a specific catheter (QDOT) during a first-time procedure to treat atrial fibrillation (AF), a type of irregular heartbeat. It aims to find which method works best for patients with recent or short-lasting AF episodes.
Paris, ParisAges 18 years+ - NCT07171463Recruiting
New ablation for paroxysmal atrial fibrillation
This trial tests a new treatment that uses two types of energy (pulsed field and radiofrequency) to fix the heart's electrical signals in people with paroxysmal atrial fibrillation (AFib that comes and goes). It aims to be more effective and safer than standard ablation alone.
Rzeszów, Podkarpackie VoivodeshipAges 18 years+ - NCT05407610Recruiting
Compare two types of nerve pain treatments for knee pain
This study compares conventional versus cooled radiofrequency treatments for long-lasting knee pain. It aims to see which method reduces pain better and helps patients function more comfortably.
AntwerpAges 18 years+ - NCT05551299RecruitingPhase 4
Non-surgical treatment for bile duct cancer using heat or light
This trial tests whether treating hilar bile duct cancer with either radiofrequency ablation (heat) or photodynamic therapy (light-activated medicine) can help patients when surgery isn’t an option. It aims to treat the tumor directly without planned surgery soon.
AachenAges 18 years+
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Common questions
- Are there clinical trials for radiofrequency ablation?
- Yes. Clin2 currently lists 114 recruiting radiofrequency ablation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a radiofrequency ablation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a radiofrequency ablation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.