Clin2
NCT07132515Possibly a fitRecruiting

Blood thinners for cirrhosis with portal vein clot

CirrhosisHCC - Hepatocellular CarcinomaPortal Vein Thrombosis

Part of Cancer, Digestive system clinical trials.

This study tests whether blood thinners (anticoagulants) are safe and effective for people with cirrhosis and a blood clot in the portal vein. It may also include people with liver cancer (HCC).

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
100 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have cirrhosis (scarring of the liver).
  • You have a blood clot in the portal vein (the main vein that brings blood to your liver).
  • Your liver function is Child-Pugh class A or B (mild to moderate damage).
  • You may also have liver cancer (HCC), but it is not required.
  • Your platelet count must be 10,000 or higher (not too low for clotting).
  • Your kidney function must be good (creatinine level 1.9 or lower).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06818279Not yet recruiting· Phase 2/Phase 3
Blood thinners for liver vein clot in cirrhosis

This trial tests whether a pill (dabigatran) or a daily injection (enoxaparin) is better at preventing new blood clots in the liver vein for people with cirrhosis. Both are blood thinners, and the study wants to see which one is safer and more effective.

New Delhi, National Capital Territory of Delhi
NCT07422701Not yet recruiting
Blood clots in the liver's main vein in cirrhosis

This study is following people with cirrhosis to see how often they get a blood clot in the liver's main vein (portal vein) and whether using blood thinners helps. If you have cirrhosis, joining this study could help doctors learn better ways to prevent and treat these clots.

Beijing, Beijing Municipality
NCT07521332Recruiting· Phase 4
Testing Apixaban to Prevent Bleeding Complications in Cirrhosis

This study tests whether a blood thinner called apixaban can safely prevent dangerous bleeding in people with cirrhosis (liver scarring) who have portal hypertension (high blood pressure in veins leading to the liver). The goal is to see if it reduces bleeding risk without causing excessive bleeding.

Hyderābād, Sindh
NCT07602062Not yet recruiting
New blood thinner for liver cirrhosis patients with variceal bleeding and portal vein clot

This trial tests a new oral blood thinner to prevent another bleeding episode in people with liver cirrhosis who have already had variceal bleeding and also have a clot in the portal vein. The goal is to see if it can safely reduce the risk of rebleeding.

Shanghai
NCT07461532Recruiting
Apixaban for late portal vein clot after spleen surgery

This trial is testing whether a blood thinner called apixaban can treat a blood clot in the main vein to the liver (portal vein) that appeared more than a year after spleen surgery in people with cirrhosis. It compares apixaban to a low-dose aspirin to see if one works better with fewer side effects.

Yangzhou, Jiangsu
NCT07461545Recruiting
Apixaban for late portal vein clot after spleen surgery

This trial tests if apixaban, a blood thinner, is more effective than aspirin at treating blood clots in the portal vein that form more than a year after laparoscopic spleen removal in people with cirrhosis and an enlarged spleen.

Yangzhou, Jiangsu

Hear when a new Cirrhosis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.