Study of SHR-1905 for chronic sinusitis with nasal polyps
Treatments studied
Part of Ear, nose & throat clinical trials.
This trial tests a new injection (SHR-1905) for people with chronic sinusitis and nasal polyps who still have symptoms despite using standard nasal spray treatments. It aims to see if the drug can reduce polyp size and improve symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 40 kg (about 88 pounds).
- You have been diagnosed with chronic sinusitis and nasal polyps, and have had symptoms for at least 4 weeks.
- You have nasal polyps in both nostrils (a doctor will confirm this with a scope).
- You have moderate to severe symptoms (a score of 30 or higher on a standard sinus questionnaire).
- You have been using a nasal steroid spray regularly for your condition.
- You have either had nasal polyp surgery in the past or have used steroid pills within the last year (or have a medical reason not to use them).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new medication called CM326 for people with long-term sinus inflammation and nasal polyps. The goal is to see if it reduces symptoms like congestion and improves quality of life. You will receive either the study drug or a placebo.
This study looks at different “immune inflammation patterns” in people with asthma and/or nasal polyps. It may help researchers better tailor future treatments by figuring out which patterns go with which symptoms.
This study tests a new medicine called AK139 (given as an injection) to reduce nasal polyps and improve breathing. It is for adults with chronic sinusitis and nasal polyps who still have symptoms despite using steroid sprays.
This study tests an injection called LP-003 that may help reduce nasal polyps and improve breathing. It's for people whose symptoms are not controlled by standard treatments like steroid sprays or surgery.
This trial tests an injectable drug called TQC2731 for people with chronic sinusitis and nasal polyps that haven't been controlled well enough by standard treatments like steroid sprays or surgery. The goal is to see if it helps reduce nasal congestion, improve sense of smell, and shrink polyps.
This study tests an experimental medication called felcorekibart, given as an injection, to see if it reduces nasal polyps and improves sinus symptoms like congestion and loss of smell. It is for adults who have had nasal polyps for at least a year and have already tried standard treatments like steroid sprays or pills, or had surgery.
Hear when a new Chronic Rhinosinusitis With Nasal Polyps trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.