MRI-guided rectal cancer preservation program
Part of Cancer, Digestive system clinical trials.
This trial uses MRI scans to guide a treatment plan for rectal cancer that may allow you to avoid surgery. The goal is to see if a combination of chemotherapy and radiation can preserve the rectum and keep the cancer from coming back.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have rectal cancer that is stage II (T3-4, N0) or stage III (any T, N1-2).
- You have not had radiation therapy to the rectal area before.
- You are generally well enough to undergo treatment (ECOG score 0-2) and your blood counts meet certain levels.
- You are able to have an MRI scan.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies a total “before-surgery” treatment plan for locally advanced rectal cancer, using MRI (a detailed scan) to help guide radiation. It may help patients by aiming to shrink the tumor and improve the chance of successful surgery.
This trial tests whether radiation therapy can be adjusted each session using MRI images to better target rectal cancer while sparing healthy tissue. It's for patients with stage II or III rectal cancer that hasn't spread to other parts of the body.
This trial tests whether combining chemotherapy with high-dose radiation guided by MRI (a special scan) can better treat low rectal cancer. It may help shrink the tumor and improve local control while targeting the tumor more precisely.
This trial tests a new way to give high-dose radiation to rectal cancer tumors while avoiding the bladder and bowels. The goal is to cure the cancer without removing the rectum, so you may keep normal bowel function.
This study looks at how an MRI “score” (mrTRG) matches how well locally advanced rectal cancer shrinks after pre-surgery chemotherapy and radiation. The goal is to use MRI results to better predict treatment response and guide care.
This trial compares two ways to preserve the rectum/avoid major surgery after radiation: a focused contact x-ray treatment versus waiting longer and then removing only a small area if needed. It may help some people keep more normal bowel function while still controlling the cancer.
Hear when a new Rectal Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.