Cell therapy for recent heart attack recovery
Part of Heart & circulation clinical trials.
This study tests an experimental cell therapy called MiSaver that may help heart muscle recover after a heart attack. It's for people whose hearts are weak and who cannot have usual procedures like stents or bypass surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 45 years or older and your body mass index (BMI) is 32 or less.
- You had a heart attack between 36 hours and 7 days ago.
- Your heart's pumping function is weakened (ejection fraction 45% or less) and you are stable without blood pressure support.
- You have a history of coronary artery disease (previous stent or bypass surgery is okay).
- You are not a candidate for standard stent or bypass surgery.
- You agree to use contraception during the study and 6 months after, and to attend follow-up visits.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether giving a combination of antioxidant vitamins (supplements) during emergency treatment for a first heart attack can reduce heart muscle damage and improve recovery. You might be eligible if you are having an emergency angioplasty for a recent heart attack.
This study is looking at certain blood markers and heart tissue changes in people who have recently had a heart attack. The goal is to understand how the heart heals and remodels after an attack, which could help improve future treatments.
This trial tests if umbilical cord stem cells, given alongside standard care, can help people who have had a major heart attack (STEMI). The cells are infused into the heart artery to possibly improve heart function. You may qualify if you are between 20 and 76, had a heart attack within the last 12 hours, and received a stent, and your heart's pumping ability is moderately reduced.
This trial tests whether injecting special cells (cell therapy) can help the heart recover in people with advanced heart failure who are getting a mechanical heart pump (LVAD). It may offer a new way to improve heart function and quality of life.
This Phase 1 study tests a treatment made from stem cells to grow heart muscle cells (“cardiomyocytes”) for people with long-lasting (chronic) heart weakness after a prior heart attack. It aims to see if the therapy can improve heart function and is safe in carefully selected patients.
This trial tests a new kind of cell therapy made from donor cells that aims to reduce inflammation and help the heart recover after a severe heart attack. It's designed for people who are in cardiogenic shock (when the heart can't pump enough blood) despite having had emergency procedures like stents or bypass surgery.
Hear when a new Acute Myocardial Infarction (AMI) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.