Stem cell treatment after heart attack
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if umbilical cord stem cells, given alongside standard care, can help people who have had a major heart attack (STEMI). The cells are infused into the heart artery to possibly improve heart function. You may qualify if you are between 20 and 76, had a heart attack within the last 12 hours, and received a stent, and your heart's pumping ability is moderately reduced.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 20 to 75 years old.
- You had a type of heart attack called STEMI within the past 12 hours and got a stent placed.
- Your heart's left ventricle pumps out between 30% and 49% of its blood (LVEF).
- Your vital signs (like blood pressure and heart rate) are stable before the infusion.
- Your lung function is good (FEV1 > 50% predicted and oxygen level at least 95% on room air).
- You have adequate blood cell counts and liver/kidney function (no severe organ problems).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 1 study tests whether an “MCRcI” stem cell treatment is safe and may improve symptoms in people with widespread coronary artery disease (clogged heart arteries). It may help those with ongoing chest pain from angina despite proper heart medications.
This trial tests whether giving specially prepared stem cells from your own blood can help your heart recover after a heart attack. You must have had a successful angioplasty or stenting within the last 4 weeks.
This study tests a new cell therapy (MiSaver) for people who have had a heart attack and whose heart is not pumping as strongly as it should. It aims to see if these cells can help the heart recover when stents or bypass surgery aren't an option.
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
This Phase 1 study tests a treatment made from stem cells to grow heart muscle cells (“cardiomyocytes”) for people with long-lasting (chronic) heart weakness after a prior heart attack. It aims to see if the therapy can improve heart function and is safe in carefully selected patients.
This trial tests whether umbilical cord stem cells given within a month after a stroke can help patients recover. It is for people with a moderate to moderately severe stroke affecting the front part of the brain.
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