Stem cell heart muscle therapy for weak heart after prior heart attack
Part of Heart & circulation clinical trials.
This Phase 1 study tests a treatment made from stem cells to grow heart muscle cells (“cardiomyocytes”) for people with long-lasting (chronic) heart weakness after a prior heart attack. It aims to see if the therapy can improve heart function and is safe in carefully selected patients.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 21 to under 80 years old
- You have had a prior heart attack and have evidence of lasting heart muscle damage (shown on imaging) from blocked heart arteries
- Your heart pumping strength (ejection fraction) is below 40% and you have heart failure symptoms in the last 6 months
- You are already on the usual “maximum” heart failure medicines at stable doses (or you have a reason you can’t take some)
- You need a cardiac catheterization (a heart procedure done through blood vessels) within about 5–10 weeks of screening
- You have an implanted defibrillator (AICD) in place, and it has not fired in the last 60 days
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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