Immunotherapy plus chemotherapy before surgery for advanced oral cancer
Part of Cancer clinical trials.
This trial tests a combination of an immunotherapy drug (adebrelimab) and two standard chemotherapy drugs (carboplatin and albumin-bound paclitaxel) before surgery for advanced oral cancer that can be removed. The goal is to see if this approach helps shrink the tumor and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with oral cavity squamous cell carcinoma (a type of head and neck cancer) and it is at stage III or IVB.
- Your tumor can be removed with surgery (it is resectable).
- You have not had cancer elsewhere before, and have not had previous anti-cancer treatment like surgery, chemotherapy, or radiation.
- You are generally in good health (able to carry out daily activities) and have adequate blood, liver, and kidney function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is testing a new combination of an immunotherapy drug (adebrelimab) plus two chemotherapy drugs (paclitaxel and carboplatin) given before surgery for advanced oral cancer. The goal is to see if this treatment can shrink the tumor and improve outcomes.
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