Clin2
NCT07833098Possibly a fitNot yet recruiting

A new medicine for hard-to-control high blood pressure

HypertensionResistant HypertensionUncontrolled Hypertension

Part of Heart & circulation clinical trials.

This study tests a new investigational medicine called VB19055 for people whose high blood pressure is not controlled even though they are already taking multiple blood pressure medications. The trial aims to see if this new drug can help lower blood pressure more effectively.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
240 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • Your systolic blood pressure (the top number) is between 135 and 170 mmHg when measured in the clinic.
  • You are currently taking at least two different blood pressure medications (including a water pill) but your blood pressure is still not well controlled, OR you are taking three or more such medications.
  • Your potassium level is in the normal range (between 3.5 and 5.0).
  • You are not pregnant or planning to become pregnant, and you agree to use highly effective birth control during the study.
  • You do not have known causes of high blood pressure like kidney artery problems or untreated thyroid disease, and you have not had major surgery in the last 6 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07654140Recruiting· Phase 2
Testing a new drug for uncontrolled high blood pressure

This trial tests a new drug called SAL0140 for people whose high blood pressure is not controlled by current treatments. It may help lower blood pressure when other medications haven't worked well enough.

Beijing, Beijing Municipality
NCT07254481Recruiting· Phase 1
Safety study of VB19055 in healthy volunteers

This trial tests a new drug (VB19055) in healthy volunteers to see how safe it is and how the body processes it. Participants will be watched closely and may help find the right dose for future studies.

Hangzhou
NCT07142356Recruiting· Phase 2
New oral medication for high blood pressure not controlled by current pills

This study tests a new medication, RTN-001, for people whose blood pressure remains high even when taking multiple blood pressure medications. The goal is to see if this drug can lower blood pressure more effectively.

Alexander City, Alabama
NCT07686120Recruiting· Phase 3
Baxdrostat for uncontrolled high blood pressure

This trial tests a new medicine called baxdrostat for people whose blood pressure stays high even when they take two or more medicines. It will be added to your current blood pressure pills to see if it helps lower your blood pressure more.

Beijing
NCT07660796Not yet recruiting· Phase 3
Blood pressure medication study for high blood pressure

This study tests a new blood pressure medication to see if it is safe and effective for people with high blood pressure. It may help lower your blood pressure and reduce health risks.

Goyang-si, Gyeonggi-do
NCT07758634Recruiting· Phase 1/Phase 2
Study of an experimental treatment for high blood pressure

This trial tests a new treatment called CTX340 for high blood pressure that is hard to control even with multiple medications. The study aims to see if it is safe and effective.

Port Orange, Florida

Hear when a new High blood pressure trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.