Alpha-1 antitrypsin deficiency in liver cancer patients
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study looks for a genetic condition called alpha-1 antitrypsin deficiency in people who have liver cancer (hepatocellular carcinoma) but do not have cirrhosis. If you have this deficiency, it might be the reason for your liver cancer, and the study may help identify more people with this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You must have a confirmed diagnosis of hepatocellular carcinoma (a type of liver cancer) from a tissue sample.
- Your liver should be either normal or have only mild to moderate scarring, not advanced cirrhosis.
- You must not have any other known cause of liver disease, such as alcohol-related liver disease, fatty liver disease (MASH), viral hepatitis, or hemochromatosis.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new blood test to help detect liver cancer (HCC) or confirm it’s not present in people with cirrhosis who are being monitored. It may help improve how doctors screen for liver cancer and decide who needs further imaging or treatment.
This study looks at blood and tissue samples from people with liver cancer to find markers that can predict how well treatment works and whether the cancer might come back. It may help doctors personalize treatment and follow-up care.
This study looks at your risk of developing liver cancer (hepatocellular carcinoma) if you have a liver condition such as NAFLD or a related disease. It aims to improve how doctors predict who might be at higher risk, so they can offer better monitoring and care.
This study tests a new way to screen for liver cancer in people with chronic liver disease, especially those with cirrhosis or significant liver scarring. It uses blood tests and imaging to catch cancer early.
This study aims to improve how doctors diagnose and treat liver cancer by combining advanced imaging tests and genetic analysis. It may help in choosing the most effective treatment for each person.
This study is looking for people with or without liver cancer to test a new way to find liver cancer early using blood or tissue samples. It aims to help catch the disease sooner.
Hear when a new Retrospective Cohort of Patients Diagnosed With HCC on Non-Cirrhotic Liver trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.