Testing a weight loss drug's effect on muscle and bone
Treatments studied
Part of Bones, joints & muscles, Genetic & congenital, Hormones & metabolism clinical trials.
This study tests a medication called tirzepatide (a type of GLP-1 drug) to see how it affects muscle and bone health during weight loss. It is for people with obesity who are not menopausal and do not have diabetes or bone disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 50 years old.
- Your body mass index (BMI) must be between 30 and 40.
- If you are female, you must not be going through menopause (you should still be having regular periods).
- You cannot have osteoporosis or be taking medications for bone loss.
- You cannot have diabetes, significant kidney or liver disease, or a history of cancer (except non-melanoma skin cancer).
- You must be willing to use a smartphone app (Lifestyle Toolkit) as part of the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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