CAR T-cell therapy for hard-to-treat autoimmune diseases
Treatments studied
Part of Immune system & allergy clinical trials.
This trial tests a type of immune cell therapy called CAR T-cells that target CD19, for people with severe autoimmune diseases that haven't improved with standard treatments. The goal is to see if it can help calm the immune system and reduce disease activity.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old.
- You have been diagnosed with one of these conditions for at least 6 months: lupus, myositis, scleroderma, pemphigus, psoriasis, rheumatoid arthritis, or ANCA vasculitis.
- Your disease is moderate to severe and has not responded well to at least 12 weeks of standard therapy.
- You must use effective birth control if you could become pregnant (women need a negative pregnancy test).
- You are able to provide medical records from the last 3 months and agree to follow the study schedule.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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