Clin2
NCT07167459Possibly a fitEnrolling by invitation

Personalized radiation for early stage lung cancer

Early-stage Peripheral Non-small Cell Lung Cancer

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a personalized radiation treatment called SBRT for early-stage non-small cell lung cancer that is located in the outer part of the lung and cannot be removed with surgery. The goal is to see if this approach works well for people who cannot have surgery or choose not to.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
251 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have a confirmed diagnosis of non-small cell lung cancer that is stage IA or IIA (early stage) and located in the outer part of the lung (at least 2 cm from the main airways or chest center).
  • You must be unable to have surgery because of poor lung function, heart problems, or similar reasons, or you have chosen not to have surgery.
  • You must be in fairly good overall health (able to care for yourself and up and about more than 50% of waking hours).
  • You must not have had previous radiation, chemotherapy, targeted therapy, or surgery for lung cancer.
  • You must not have any other active cancer (except certain skin cancers or cervical pre-cancer that was treated within the last 5 years).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05802654Not yet recruiting
Very high-dose focused radiation for early lung cancer

This study tests whether a single, very high-dose focused radiation treatment can control early-stage lung cancer. It may help people who can’t or prefer not to have surgery, by delivering precise radiation to the tumor while aiming to spare nearby tissue.

Beijing, Beijing Municipality
NCT05349552Recruiting
Radiation for lung or chest cancers in specific locations

This trial studies how safe and effective a type of focused radiation called SBRT is for cancer tumors in certain chest locations. It’s meant for people whose tumor is small (up to 5 cm) and who don’t have widespread, uncontrolled spread.

Beijing, Beijing Municipality
NCT07379398Not yet recruiting· Phase 2
Immunotherapy with radiation for early-stage lung cancer

This trial tests a combination of two immunotherapy drugs (iparomlimab and tuvonralimab) with stereotactic body radiation therapy (SBRT) for people with early-stage non-small cell lung cancer. The goal is to see if this treatment can help shrink or control the cancer before surgery.

Tianjin, Tianjin Municipality
NCT05974475Recruiting
Personalized modeling during targeted lung radiation for early cancer

This trial studies how detailed tests (“multi-omics” modeling) can improve how doctors plan and deliver stereotactic body radiotherapy (SBRT) for early-stage non-small cell lung cancer. It may help make treatment planning more precise for cancers in stages I–II.

Milan, Italy
NCT06542159Recruiting· Phase 2
Adaptive radiation for early-stage lung cancer or small metastases

This trial tests a more precise radiation technique (stereotactic body radiotherapy) for early-stage lung cancer or small lung tumors. It aims to reduce side effects by eliminating the usual safety margin around the tumor.

Guangzhou, Guangdong
NCT07441941Recruiting
Single dose radiation for early-stage or limited lung tumors

This trial tests how a single, high-dose radiation treatment (called SBRT) affects quality of life and outcomes for people with certain lung tumors. It's for adults with early-stage non-small cell lung cancer or a lung tumor that has spread from another cancer, as long as the tumor is small and in the outer part of the lung.

Montpellier, ICM

Hear when a new Early-stage Peripheral Non-small Cell Lung Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.