Study of rocuronium timing and heart function during anesthesia
Part of Brain & nervous system clinical trials.
This trial tests how fast the muscle relaxant rocuronium works during surgery, and whether a patient's heart function affects its onset. It may help doctors give the right dose at the right time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be having general anesthesia with an arterial line (a small tube in an artery) and the muscle relaxant rocuronium at a participating hospital.
- Your surgery or procedure must be expected to last at least 1.5 hours.
- You cannot have any condition that makes rocuronium unsafe for you, such as a muscle or nerve disorder.
- You cannot have certain health problems including kidney failure, chronic liver disease, epilepsy, or atrial fibrillation (an irregular heartbeat).
- You must be able to consent for yourself and not need an interpreter for hospital communication.
- You must not be pregnant, breastfeeding, or taking lithium or the antibiotic gentamicin before your procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two medicines—remifentanil and rocuronium—to see which helps doctors place a breathing tube more easily during anesthesia. It may help you if you are having routine surgery and need a tube for breathing support.
This trial investigates whether giving rocuronium (a muscle relaxant) before the main anesthetic can make muscles relax faster and affect heart rate and blood pressure during the start of general anesthesia. It aims to improve safety and smoothness of the process for people having planned surgery with a breathing tube.
This trial compares two muscle relaxants, rocuronium and cisatracurium, to see which causes fewer complications in people with chronic kidney disease (not on dialysis) who need general anesthesia. If you have kidney disease and are having surgery that requires a breathing tube, this study may help determine the safer drug for you.
This trial tests if different levels of muscle relaxation during abdominal surgery affect lung function and breathing problems after surgery. It may help patients who are having open abdominal surgery under general anesthesia lasting over an hour.
This study compares a new muscle relaxant medication with a standard one to see how well they work for placing a breathing tube and maintaining muscle relaxation during surgery. It aims to find a safer or more effective option for patients undergoing general anesthesia.
This trial tests whether using a lower dose of rocuronium (a muscle relaxant used during surgery) works safely during spine surgery when doctors are monitoring your nerves. The goal is to keep your nerves working properly during surgery while using less medication.
Hear when a new Muscle Relaxants trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.