CUE-101 plus pembrolizumab for HPV+ throat cancer
Treatments studied
Part of Cancer clinical trials.
This trial tests a new drug called CUE-101 combined with a standard immunotherapy (pembrolizumab) for people with HPV-16 positive head and neck cancer that cannot be removed with surgery. The goal is to see if this combination can shrink or control the cancer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a newly diagnosed HPV-16 positive head and neck cancer (specifically in the oropharynx) that cannot be removed with surgery.
- You must have a specific genetic marker on your immune cells called HLA-A*02:01.
- You must have a tumor that can be seen and measured on a scan (like a CT or MRI).
- You cannot have had radiation or chemotherapy for this cancer before.
- You must be in generally good health (able to do daily activities) and have normal organ function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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