Tadalafil for early Alzheimer's and memory loss
Treatments studied
Part of Brain & nervous system, Mental health clinical trials.
This study tests whether a daily pill (tadalafil, a type of medicine usually used for blood pressure or erectile dysfunction) can help people with early Alzheimer's or mild memory problems. It aims to see if this drug can improve memory and slow down the disease, with the help of regular checkups and brain scans.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are at least 50 years old and have been diagnosed with mild cognitive impairment (MCI) or early Alzheimer's disease.
- You can think clearly enough to give your own permission to join, and you have a family member or friend who can attend visits with you as a study partner.
- You score between 22 and 28 on a simple memory and thinking test called the MMSE.
- You are fluent in English and are likely to be able to complete all the study visits and tests.
- You do not have major heart problems, recent stroke, severe kidney or liver disease, or other serious health conditions that could make the study unsafe.
- You are not taking nitrates (heart medications) or other medicines that could interfere with the study drug.
- You are not a woman who could become pregnant, and you have no allergies to the study drug or to the MRI contrast dye.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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