Clin2
NCT07177378Possibly a fitEnrolling by invitation

Double flap closure for jaw bone damage from medication

Osteomyelitis of Jaw

Part of Bones, joints & muscles, Mouth & dental clinical trials.

This trial tests a surgical technique using a double tissue flap to close the jawbone in patients with medication-related osteonecrosis of the jaw (MRONJ). The goal is to improve healing and reduce complications.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
20 people
Ages
Any age
Study type
Interventional

Who can take part

  • You have been diagnosed with medication-related osteonecrosis of the jaw (MRONJ).
  • You have not had radiation therapy to the head or neck.
  • You need surgical treatment, not just conservative care like mouth rinses or antibiotics.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07590427Not yet recruiting
Rebuilding mouth floor after surgery

This trial tests a surgical technique to repair small to medium-sized tissue defects in the floor of the mouth using a flap from nearby muscle and bone lining. It aims to improve healing and function after removing tumors or other lesions.

Alexandria, Azarita
NCT06984107Not yet recruiting
Testing a healing gel for jaw bone medication-related damage

This trial tests whether a special gel made of polynucleotides and hyaluronic acid (molecules that help tissue repair) can improve healing after jaw surgery for early-stage medication-related osteonecrosis. The gel is applied during surgery to support the bone and gum healing.

NCT06419010Not yet recruiting
Using your own blood clot to help jaw surgery heal

This trial tests whether a special dressing made from your own blood (called L-PRF) can help your jaw heal better after surgery for medication-related bone damage. It's for people who need surgery for this condition and aims to improve recovery.

Bordeaux
NCT07435259Recruiting
Treating jaw bone problems around dental implants: keep or remove?

This study compares two ways to treat a jaw bone problem caused by medications (called MRONJ) when it happens around a dental implant. One option is to keep the implant and treat the bone, the other is to remove the implant. The goal is to see which approach leads to better healing.

Seoul, Seoul
NCT05795647Recruiting· Phase 2
Testing pentoxifylline and vitamin E for jaw bone damage

This trial tests a combination of medicines (pentoxifylline and tocopherol, a form of vitamin E) to treat damage to the jaw bone caused by bone-strengthening drugs. If you have Stage 2 MRONJ and meet other criteria, this treatment may help heal the bone.

Limoges
NCT07691892Not yet recruiting
Bone-strengthening drugs and dental procedure safety

This study looks at people taking bone-strengthening drugs (like bisphosphonates or denosumab) who need dental work, such as tooth extraction or root canals. It aims to reduce the rare risk of jaw bone damage (osteonecrosis of the jaw) and help dentists and doctors choose the best timing for procedures.

Hear when a new Osteomyelitis of Jaw trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.