Probiotics to improve gut health after stem cell transplant
Part of Blood & lymphatic, Digestive system, Immune system & allergy clinical trials.
This trial tests whether taking probiotics made from your own and your donor's bacteria can help prevent or reduce gut problems (like diarrhea) after a stem cell transplant. It may help your intestines recover and feel better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are older than 50 years.
- You are scheduled to receive a stem cell transplant from a half-matched donor (haploidentical).
- You are generally able to care for yourself (ECOG score 2 or less).
- You do not have an active infection or fever in the last 48 hours.
- You do not have certain gut diseases like ulcerative colitis, Crohn's disease, or irritable bowel syndrome.
- You have not taken antibiotics in the last 7 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study looks at changes in your gut bacteria (microbiome) around the time of stem cell transplant. The goal is to understand how these bacteria relate to transplant outcomes, which may help doctors improve care in the future.
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This study tests whether transplanting healthy donor stool into the gut can help children and young adults with ongoing digestive issues after a stem cell transplant. It may improve symptoms like diarrhea or the need for feeding tubes.
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