Testing a clip procedure for heart valve leak in heart failure
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a procedure called transcatheter edge-to-edge repair (TEER) for people with a specific type of heart valve leak (functional mitral regurgitation) that is causing heart failure symptoms. The procedure is less invasive than open-heart surgery and aims to improve symptoms and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have significant mitral regurgitation (leaking of the mitral valve) that worsens with exercise.
- You have symptoms of heart failure (such as shortness of breath, fatigue, or fluid retention) despite being on optimal heart failure medications.
- You have been hospitalized for heart failure in the last year or have elevated BNP/NT-proBNP levels within the last 3 months.
- Your ejection fraction (a measure of heart pumping function) is 20% or higher.
- You are able to walk for 6 minutes, with any limitation mainly due to heart-related issues.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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