Mitral valve repair for leak that worsens with exercise
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a procedure to fix a leaky mitral valve that only becomes severe during exercise. It may help people with symptoms like shortness of breath or fatigue who haven't responded to standard heart medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a mild to moderate mitral valve leak at rest that becomes severe when you exercise.
- You have symptoms like shortness of breath or fatigue (NYHA class II-IV) or have been hospitalized for heart failure in the past year.
- Your heart failure medications have been stable for at least 30 days.
- You are 18 years or older.
- You are able to exercise (for the stress test).
- You do not have severe kidney disease, recent heart attack or stroke, or other major heart valve problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a procedure to fix a leaky mitral valve that occurs because the heart muscle is weak or enlarged, and which gets worse with activity. The procedure aims to reduce the leak and improve symptoms and quality of life in people with heart failure.
This trial tests whether repairing a leaky heart valve (mitral valve) can help people with heart failure feel better and live longer, even when standard heart failure medicines are not working well. The repair is done through a small tube in a blood vessel, avoiding open-heart surgery.
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
This trial tests a new device called the Capstan system to fix a leaky mitral valve (mitral regurgitation) without open-heart surgery. It may help people whose valve leak is moderate to severe and still have symptoms despite medicines.
This trial tests a minimally invasive procedure to fix a leaky mitral valve in people with ATTR-CM. The procedure, called edge-to-edge repair, uses a catheter to clip the valve, which may improve symptoms and quality of life.
This trial is testing a new device to help people with severe mitral regurgitation (a leaky heart valve) who cannot have open-heart surgery or a valve clip. The device is placed using a thin tube through a blood vessel, and aims to improve symptoms and quality of life.
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