Home breathing machine for severe COPD patients
Part of Lungs & breathing clinical trials.
This trial tests whether using a non-invasive ventilator (a breathing machine with a mask) at home can help people with severe COPD who have high carbon dioxide levels in their blood. It aims to improve breathing and reduce the need for hospital visits.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be over 18 years old
- Your COPD must be severe (stage 3 or 4), confirmed by a breathing test showing low lung function
- Your blood carbon dioxide level must be high (60 mmHg or more) and stay high for at least 2 weeks after recovering from a flare-up, even with optimal medication or oxygen therapy
- You cannot have other serious breathing problems like sleep apnea, being very overweight (BMI over 30), collapsed lung, large lung bullae, advanced lung scarring, chest wall disorders, or muscle/nerve diseases
- You must not have used a breathing tube or tracheostomy in the last 2 months
- You should not be using addictive narcotic medications
- You must not have serious health issues like cancer, advanced liver or kidney disease
- You cannot be pregnant
- You must be willing and able to use the breathing machine at home (and have family support)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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