Study of orelabrutinib and rituximab with optional stem cell transplant for mantle cell lymphoma
Treatments studied
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial is testing a combination of two targeted drugs, orelabrutinib and rituximab, as a first treatment for mantle cell lymphoma (MCL). Some patients may also get a stem cell transplant. The goal is to see how well this approach works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have mantle cell lymphoma (MCL) that hasn't been treated yet.
- You are at least 14 years old.
- Your lymphoma is stage II, III, or IV and needs systemic therapy.
- You have at least one tumor that can be measured on scans.
- Your blood counts and liver/kidney function are within certain limits.
- Your doctor believes you will live more than 12 weeks.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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